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Search Results for " irak 4 "

Targets Recommended: IRAK

45

抑制剂 & 化合物

1

天然产物

32

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T2457	IRAK-1-4 Inhibitor I IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor	IRAK	Immunology/Inflammation; NF-κB
	IRAK-1-4 Inhibitor I 是一种IRAK1/4双重抑制剂，其IC50分别为 0.2 μM 和 0.3 μM。
T9631	IRAK-4 protein kinase inhibitor 2	IRAK	Immunology/Inflammation; NF-κB
	IRAK-4 protein kinase inhibitor 2 是有效的白介素 1 受体相关激酶 4 抑制剂，IC50为 4 μM。它在与炎症和免疫相关的疾病领域有研究价值。
T11673	IRAK4-IN-4	IRAK; cGAS	Immunology/Inflammation; NF-κB
	IRAK4-IN-4 （化合物 15）是白介素-1 受体相关激酶抑制剂，IC50为 2.8 nM。它还抑制环 GMP-AM 合酶，IC50为 2.1 nM。
T4140	IRAK4-IN-1	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-1 是白细胞介素-1 受体相关激酶 4 抑制剂(IC50:7 nM)。
T11672	IRAK inhibitor 4	Others	Others
	IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.
T11671	IRAK inhibitor 4 trans	SGLT	GPCR/G Protein
	IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers to its specific molecular configuration.
T4299	AS-2444697	IRAK	Immunology/Inflammation; NF-κB
	AS2444697 是一种口服有效的IRAK-4抑制剂，IC50为 21 nM。它对人和大鼠 IRAK-4 活性具有抑制作用。它通过抗炎作用表现出肾脏保护作用。
T39901	PROTAC IRAK4 degrader-4 PROTAC IRAK4 degrader-4
	PROTAC IRAK4 degrader-4 (US20190192668A1, compound I-127) is a Cereblon-based PROTAC specifically designed to target and degrade interleukin-1 receptor-associated kinase 4 (IRAK4).
T62714	IRAK4-IN-20 BAY-1834845	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-20 是一种有效的、具有口服活性的 IRAK4 抑制剂（ IC50 ： 3.55 nM）。 IRAK4-IN-20 ，具有抗缓解炎症、抗肿瘤和抗癌作用，常用于治疗急性呼吸窘迫综合征 (ARDS) 。
T63388	IRAK4-IN-8	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-8 (VI-177) 是一种 IRAK4 抑制剂，可用于研究与癌症和炎症相关的疾病。
T39902	PROTAC IRAK4 degrader-5 PROTAC IRAK4 degrader-5
	PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.
T39920	PROTAC IRAK4 degrader-3 PROTAC IRAK4 degrader-3
	PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.
T39903	PROTAC IRAK4 degrader-6 PROTAC IRAK4 degrader-6
	PROTAC IRAK4 degrader-6 is a potent Cereblon-based compound designed to degrade interleukin-1 receptor-associated kinase 4 (IRAK4).
T5354	IRAK4-IN-7 CA-4948	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂，口服有活性。它可用于研究癌症以及炎症疾病。
T14367	AZ1495	IRAK; CDK; Haspin Kinase	Cell Cycle/Checkpoint; Immunology/Inflammation; NF-κB
	AZ1495 是一种口服有活性的白介素-1受体相关激酶 4(IRAK4)抑制剂，能够作用于 IRAK4 (IC50:5 nM)和 IRAK1 (IC50:23 nM)。可用于研究突变型 MYD88L265P 弥漫性 B 细胞淋巴瘤 (DLBCL) 。
T24174	IRAK4-IN-16
	IRAK4-IN-16 (compound 4) 是一种强效的白细胞介素 -1 受体相关激酶 4(IRAK4) 抑制剂，IC50为 2.5 nM。IRAK4-IN-16 对 OCI-LY10、TMD8、Ramos 和 HT 细胞表现出细胞毒性活性，其 IC50分别为 0.2、0.2、0.6 和 2.7 μM。
T11674	IRAK4-IN-6	Others	Others
	IRAK4-IN-6 是一种选择性的、口服有效的IRAK 抑制剂，IC50为 4 nM，靶向 MyD88 L265P 突变型弥漫性大 B 细胞淋巴瘤。
T13843	PROTAC IRAK4 ligand-1	Others	Others
	PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4.
T13842	PROTAC IRAK4 degrader-1	Others	Others
	PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).
T63278	IRAK4-IN-14
	IRAK4-IN-14 是选择性的、有效的、口服具有活力的 IRAK4 抑制剂 (IC50: 0.003 μM)，在大鼠和小鼠中具有出良好的 PK 参数。IRAK4-IN-14 与 Acalabrutinib 联合使用对 MyD88/CD79 双突变体 ABC-DLBCL 表现出协同体外作用。
T62950	IRAK4-IN-18
	IRAK4-IN-18 是一种白介素 1 受体相关激酶 4 (IRAK4) 的有效抑制剂 (IC50: 15 nM)。IRAK4-IN-18 能够抑制 THP 和 DC 细胞中 LPS 诱导的 IL23 产生，阻断关节炎模型大鼠的关节炎发展。IRAK4-IN-18 可用于研究关节炎疾病。
T79448	IRAK4-IN-26	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-26（Compound 21）是IRAK4的有效抑制剂，IC50值为6.2 nM。该化合物的口服生物利用度达21%，主要用于研究炎症和自身免疫性疾病。
T79337	IRAK4-IN-28	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-28（compound 42）是口服活性的IRAK4抑制剂，具有8.9 nM的IC50值。该化合物对IRAK4的结合亲和力高，Kd值为0.58 nM，适用于炎症和自身免疫性疾病研究。
T79485	IRAK4-IN-27	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-27（Compound 22）为高效选择性IRAK4抑制剂，具IC50值8.7 nM。该化合物能够抑制含MYD88L265P突变的DLBCL细胞系生长并促进其细胞凋亡(apoptosis)，适用于弥漫大B细胞淋巴瘤(DLBCL)的研究。
T62850	IRAK4-IN-13
	IRAK4-IN-13 (compound 21) 是一种选择性的、有效的 IRAK4 抑制剂 (IC50: 0.6 nM)。IRAK4-IN-13 具有高代谢清除率，人肝微粒体 (HLM) 固有清除率为 96 μL/min/mg。
T63315	IRAK4-IN-19
	IRAK4-IN-19 是白介素 1 受体相关激酶 4 (IRAK4) 的有效抑制剂 (IC50: 4.3 nM)。IRAK4-IN-19 能够阻碍 THP 和 DC 细胞中 LPS 诱导的 IL23 产生，抑制关节炎模型大鼠的关节炎发展。IRAK4-IN-19 能够用于研究关节炎疾病。
T61767	IRAK4-IN-17
	IRAK4-IN-17 (Compound 5) is a highly potent inhibitor of IRAK4, exhibiting an impressive IC50 value of 1.3 nM [1]. This compound is particularly valuable for research focused on large B-cell lymphoma (DLBCL) [1].
T63262	IRAK4-IN-15
	IRAK4-IN-15 是选择性的、有效的 IRAK4 抑制剂 (IC50: 0.002 μM)，具有良好的人类 PK 预测且具有低内在清除率。IRAK4-IN-15 与 Acalabrutinib 联用对 MyD88/CD79 双突变体 ABC-DLBCL 的表现出强大的协同体外活性。
T61734	IRAK4-IN-9
	IRAK4-IN-9 (compound 73) is a highly potent inhibitor of IRAK4, displaying an impressive IC50 value of 1.5 nM. By blocking MyD88-dependent signaling, IRAK4-IN-9 exhibits promising potential for the investigation of inflammatory diseases, autoimmune diseases, and cancer [1].
T62989	IRAK4-IN-12
	IRAK4-IN-12 (compound 37) 是一种 IRAK4 的有效抑制剂 (IC50: 0.015 μM)，具有细胞 pIRAK4 效力 (IC50: 0.5 μM)。
T63558	IRAK4-IN-21
	IRAK4-IN-21 是选择性的、口服具有活力的、强效的 IRAK4 抑制剂，能够作用于 IRAK4 (IC50: 5 nM) 和 TAK1 (IC50: 56 nM)。IRAK4-IN-21 对 IL-23 的产生表现出有效的抑制作用，其 IC50值为0.17 μM。IRAK4-IN-21 能够用于研究自身免疫性疾病，如斑块状银屑病和银屑病关节炎。
T78744	IRAK4-IN-24	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-24（compound 16）是IRAK4高效抑制剂，显示高Cl及较低口服生物可用性，适用于炎症与自身免疫性疾病研究。
T60899	IRAK4-IN-11
	IRAK4-IN-11 (compound 6) 是 IRAK4的有效抑制剂，IC50值为 0.008 μM。IRAK4-IN-11 表现出细胞 pIRAK4 效力，IC50值为 0.19 μM。
T63559	IRAK4-IN-22
	IRAK4-IN-22 是选择性的、口服具有活力的、强效的 IRAK4 抑制剂，能够作用于 IRAK4 (IC50: 3 nM) 和 TAK1 (IC50: 17 nM)。IRAK4-IN-21 对 IL-23 的产生表现出有效的抑制作用，其 IC50值为0.10 μM。IRAK4-IN-21 能够用于研究自身免疫性疾病，如斑块状银屑病和银屑病关节炎。
T79447	IRAK4-IN-25	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-25（化合物38）是口服活性IRAK4抑制剂，具有低清除率（Cl=12 mL/min/kg）和IC50值为7.3 nM。它能抑制促炎细胞因子产生，表现出良好的体外安全性和ADME特性。IRAK4-IN-25主要用于研究炎症和自身免疫性疾病。
T61931	IRAK4-IN-10
	IRAK4-IN-10 (compound 75) 是有效的 IRAK4抑制剂（IC50为 1.5 nM），对 MyD88 依赖的信号通路具有阻断作用。IRAK4-IN-10 在炎症性疾病、自身免疫性疾病和癌症中具有研究的潜力。
T74062	PROTAC IRAK4 degrader-2
	PROTACIRAK4 degrader-2 (Compound 9) 是一种 PROTACIRAK4降解剂，在外周血单个核细胞 (PBMC) 中，降解 IRAK4，DC50为 151 nM。PROTACIRAK4 Degrader-2 在 PBMC 细胞中诱导 IRAK4蛋白水平降低，DC50为 36 nM。PROTACIRAK4 degrader-2 还抑制 PBMC 中多种细胞因子释放。
T74411	PROTAC IRAK4 degrader-7
	PROTACIRAK4 degrader-7 (Compound I-417) 是一种具有口服活性的 PROTACIRAK4降解剂，具有抗肿瘤效果。
T79097	PROTAC IRAK4 degrader-8	IRAK	Immunology/Inflammation; NF-κB
	PROTAC-IRAK4分解剂-8（化合物2）是针对IRAK4设计的PROTAC，表现出15.5 nM的IC50值。
T81378	PROTAC IRAK4 ligand-3	PROTACs	PROTAC
	PROTACIRAK4 ligand-3 为 PROTACIRAK4 degrader-7 配体，适用于癌症研究领域。
T7368	IRAK inhibitor 2 IRAK-IN-2	IRAK	Immunology/Inflammation; NF-κB
	IRAK inhibitor 2 (IRAK-IN-2) 是一种有效的白细胞介素1受体相关激酶4（IRAK-4）抑制剂,具有潜在的抗癌和抗癌活性，可用于研究炎症相关性疾病。
T5094	IRAK inhibitor 1	IRAK; JNK	Immunology/Inflammation; MAPK; NF-κB
	IRAK inhibitor 1 是IRAK-4抑制剂(IC50:216 nM)，微弱抑制 JNK-1 (IC50:3.801 μM)和 JNK-2(IC50>10 μM)。
T5110	IRAK inhibitor 6	IRAK	Immunology/Inflammation; NF-κB
	IRAK inhibitor 6 是白细胞介素-1受体相关激酶-4的抑制剂(IC50:160 nM)。
T60012	HS-243	IRAK; MAPK; CDK	Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK; NF-κB
	HS-243 是 IRAK-4 和 IRAK-1 的抑制剂，IC50 分别为 20 和 24 nM。 HS-243 显示出抗炎和抗癌活性。
T62473	Edecesertib
	Edecesertib (GS-5718) 是一种选择性的、口服具有活力的 IRAK-4 抑制剂，表现出抗炎活性。Edecessertib 能够用于研究类风湿性关节炎 (RA) 和红斑狼疮 (LE)。

化合物

IRAK-1-4 Inhibitor I

Cat.No: T2457

Synonym: IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor

Target: IRAK

IRAK-4 protein kinase inhibitor 2

Cat.No: T9631

Target: IRAK

Cat.No: T11673

Target: IRAK, cGAS

Cat.No: T4140

Target: IRAK

IRAK inhibitor 4

Cat.No: T11672

Target: Others

IRAK inhibitor 4 trans

Cat.No: T11671

Target: SGLT

Cat.No: T4299

Target: IRAK

PROTAC IRAK4 degrader-4

Cat.No: T39901

Synonym: PROTAC IRAK4 degrader-4

Cat.No: T62714

Synonym: BAY-1834845

Target: IRAK

Cat.No: T63388

Target: IRAK

PROTAC IRAK4 degrader-5

Cat.No: T39902

Synonym: PROTAC IRAK4 degrader-5

PROTAC IRAK4 degrader-3

Cat.No: T39920

Synonym: PROTAC IRAK4 degrader-3

PROTAC IRAK4 degrader-6

Cat.No: T39903

Synonym: PROTAC IRAK4 degrader-6

Cat.No: T5354

Synonym: CA-4948

Target: IRAK

Cat.No: T14367

Target: IRAK, CDK, Haspin Kinase

Cat.No: T24174

Cat.No: T11674

Target: Others

PROTAC IRAK4 ligand-1

Cat.No: T13843

Target: Others

PROTAC IRAK4 degrader-1

Cat.No: T13842

Target: Others

Cat.No: T63278

Cat.No: T62950

Cat.No: T79448

Target: IRAK

Cat.No: T79337

Target: IRAK

Cat.No: T79485

Target: IRAK

Cat.No: T62850

Cat.No: T63315

Cat.No: T61767

Cat.No: T63262

Cat.No: T61734

Cat.No: T62989

Cat.No: T63558

Cat.No: T78744

Target: IRAK

Cat.No: T60899

Cat.No: T63559

Cat.No: T79447

Target: IRAK

Cat.No: T61931

PROTAC IRAK4 degrader-2

Cat.No: T74062

PROTAC IRAK4 degrader-7

Cat.No: T74411

PROTAC IRAK4 degrader-8

Cat.No: T79097

Target: IRAK

PROTAC IRAK4 ligand-3

Cat.No: T81378

Target: PROTACs

IRAK inhibitor 2

Cat.No: T7368

Synonym: IRAK-IN-2

Target: IRAK

IRAK inhibitor 1

Cat.No: T5094

Target: IRAK, JNK

IRAK inhibitor 6

Cat.No: T5110

Target: IRAK

Cat.No: T60012

Target: IRAK, MAPK, CDK

Cat.No: T62473

Cat. No.	Product Name	Target	Signaling Pathways
T4700	1,3,5-Trihydroxy-4-prenylxanthone
	1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 valu

天然产物

1,3,5-Trihydroxy-4-prenylxanthone

Cat.No: T4700

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04483	IRAK4 Protein, Human, Recombinant (His) IPD1,NY-REN-64,REN64,interleukin-1 recepto...	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ...
TMPY-00749	FGF-2 Protein, Human, Recombinant fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF	Human	E. coli
	FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPJ-00864	VEGF165 Protein, Human, Recombinant Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子,VEGF...	Human	HEK293 Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi) 血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,VPF,...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04911	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated vascular endothelial growth factor A,血管内皮生长因子	Human,Cynomolgus	HEK293 Cells
	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated LCA,LY5,EC 3.1.3.48,CD45,L-CA,T200,CD4...	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,VAS,MVCD1,...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04471	APEG1 Protein, Human, Recombinant (His) SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG...	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi) CD45R,LY5,EC 3.1.3.48,B220,CD45,T...	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPJ-01333	TEM8/ANTXR1 Protein, Human, Recombinant (His) ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax Toxin Rec...	Human	HEK293 Cells
	Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPY-05598	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated SIGLEC2,SIGLEC-2,CD22 molecule	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4.
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc) Amyloid Precursor,Amyloid Precursor Protein 695,APP695	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPY-04754	CASK Protein, Human, Recombinant CMG,LIN2,MRXSNA,CAMGUK,calcium/calmodulin-dependent serine p...	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-00225	CLEC9A Protein, Mouse, Recombinant (hFc) C-type lectin domain family 9, member A,9830005G06Rik,DNGR-1	Mouse	HEK293 Cells
	CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4.
TMPY-01117	MRAP Protein, Human, Recombinant (hFc) FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...	Human	HEK293 Cells
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPJ-00233	CD200R1/CRTR2 Protein, Human, Recombinant (His) Cell Surface Glycoprotein CD200 Receptor 1,OX2R,MOX2R,CD200 ...	Human	HEK293 Cells
	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytopla...
TMPK-00702	ANTXR2 Protein, Human, Recombinant (His) cI-35,Antxr2,JHS,CMG-2,CMG2,JHF,HFS,ISH	Human	HEK293 Cells
	The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultured in vitro. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His) IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform...	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-01823	PTK9 Protein, Human, Recombinant MGC41876,twinfilin actin binding protein 1,A6,MGC23...	Human	E. coli
	PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4.
TMPY-00119	FLT1 Protein, Human, Recombinant (hFc) VEGFR1,VEGFR-1,fms-related tyrosine kinase 1,FLT-1,FLT	Human	HEK293 Cells
	FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
TMPY-04563	CASK Protein, Human, Recombinant (His & GST) calcium/calmodulin-dependent serine protein kinase (MAGUK fa...	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4.
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His) CASP10,FAS-Associated Death Domain Protein Interleukin-1B-Co...	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca...
TMPY-01822	PTK9 Protein, Human, Recombinant (His & GST) PTK9,MGC41876,A6,MGC23788,twinfilin actin binding p...	Human	E. coli
	PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
TMPY-04565	SRPK3 Protein, Human, Recombinant (His & GST) MSSK1,MGC102944,STK23,MSSK-1,SRSF protein ...	Human	Baculovirus Insect Cells
	Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-...
TMPJ-01188	CORO6 Protein, Human, Recombinant (His) Coronin-6,Clipin-E,CORO6	Human	E. coli
	Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are a family of conserved actin-binding proteins originally identified in the actin-rich structure of the amoeba Dictyostelium discoideum . To date, seven members of coronins have been identified in mammals, and most exhibit tissue-specific distribution patterns. Coronin 6 is promin...
TMPY-01933	CHI3L2 Protein, Human, Recombinant (His) YKL-39,CHIL2,chitinase 3 like 2,YKL39	Human	HEK293 Cells
	Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, followed by synoviocytes, lung and heart. YKL-39/CHI3L2 is not detected in spleen, pancreas, and liver. YKL-39/CHI3L2 may also be expressed in developing brain and placenta. YKL-39/CHI3L2, a cartilage-related protein, is found to induce arthritis accompanied by pathologic changes in b...
TMPJ-00410	CD45R0 Protein, Human, Recombinant (His) CD45 antigen,L-CA,protein tyrosine phosphatase, rec...	Human	HEK293 Cells
	CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPY-00711	CD45 Protein, Human, Recombinant (hFc) GP180,L-CA,LY5,T200,protein tyrosine phosphatase, receptor t...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4.
TMPY-00380	ANTXR2 Protein, Human, Recombinant (hFc) HFS,JHF,anthrax toxin receptor 2,ISH,CMG-2,CMG2	Human	HEK293 Cells
	ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4.
TMPK-01362	SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated MYD1,SIRP α V4,PTPNS1,BIT,SHPS1,SIRP alpha,SHPS-1,S...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01356	SIRP alpha V4 Protein, Human, Recombinant (His & Avi) BIT,SIRP α V4,MFR,SHPS1,SIRPA,SIRP α,P84,M...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

IRAK4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04483

Species: Human

Expression System: Baculovirus Insect Cells

FGF-2 Protein, Human, Recombinant

Cat.No: TMPY-00749

Species: Human

Expression System: E. coli

VEGF165 Protein, Human, Recombinant

Cat.No: TMPJ-00864

Species: Human

Expression System: HEK293 Cells

VEGF165 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00823

Species: Human

Expression System: HEK293 Cells

VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-04911

Species: Human,Cynomolgus

Expression System: HEK293 Cells

NT5C3A/NT5C3 Protein, Human, Recombinant

Cat.No: TMPY-02893

Species: Human

Expression System: E. coli

CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00424

Species: Human

Expression System: HEK293 Cells

VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00822

Species: Human

Expression System: HEK293 Cells

APEG1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04471

Species: Human

Expression System: E. coli

CD45 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00423

Species: Human

Expression System: HEK293 Cells

TEM8/ANTXR1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01333

Species: Human

Expression System: HEK293 Cells

Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-05598

Species: Human

Expression System: HEK293 Cells

Amyloid Precursor Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00782

Species: Human

Expression System: HEK293 Cells

CASK Protein, Human, Recombinant

Cat.No: TMPY-04754

Species: Human

Expression System: Baculovirus Insect Cells

CLEC9A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00225

Species: Mouse

Expression System: HEK293 Cells

MRAP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01117

Species: Human

Expression System: HEK293 Cells

CD200R1/CRTR2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00233

Species: Human

Expression System: HEK293 Cells

ANTXR2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00702

Species: Human

Expression System: HEK293 Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

Cat.No: TMPY-01033

Species: Human

Expression System: HEK293 Cells

PTK9 Protein, Human, Recombinant

Cat.No: TMPY-01823

Species: Human

Expression System: E. coli

FLT1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00119

Species: Human

Expression System: HEK293 Cells

CASK Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04563

Species: Human

Expression System: Baculovirus Insect Cells

Caspase-10 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01256

Species: Human

Expression System: E. coli

PTK9 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01822

Species: Human

Expression System: E. coli

SRPK3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04565

Species: Human

Expression System: Baculovirus Insect Cells

CORO6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01188

Species: Human

Expression System: E. coli

CHI3L2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01933

Species: Human

Expression System: HEK293 Cells

CD45R0 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00410

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00711

Species: Human

Expression System: HEK293 Cells

ANTXR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00380

Species: Human

Expression System: HEK293 Cells

SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01362

Species: Human

Expression System: HEK293 Cells

SIRP alpha V4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01356

Species: Human

Expression System: HEK293 Cells

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